Inflammation is a part of the body’s defence mechanism that holds a significant role in the healing process. When the body identifies a trespasser, it sets in for a biological response to eliminate it. The attacker can be a foreign substance, such as a thorn, an irritant, or a pathogen. Bacteria, viruses, fungus, and other microorganisms are some of the pathogens that cause infections. At times the body mistakenly identifies its own cells or tissues as harmful, and this reaction results in autoimmune diseases such as type 1 diabetes. Medical experts state that inflammation can lead to the development of an extensive range of chronic diseases including metabolic syndromes, such as type 2 diabetes, obesity, and heart disease.
Acute inflammation and Chronic inflammation

Types Of Inflammation

There are two types of inflammation -acute and chronic.

Acute Inflammation

Any injury or illness can trigger acute or short-term, inflammation. There are five vital signs of acute inflammation which include:

Pain: It occurs recurrently or when a person touches the affected region.

Redness: This develops due to increased blood flow to the capillaries in the affected area.

Loss of function: A person may find it difficult to move a joint, breathing, sensing odour and many more.

Swelling: A condition called oedema that results in fluid build-up.

Heat: Increased blood flow resulting in a feeling of warmth in the affected region.

However, these signs are not always seen and sometimes inflammation is silent, without any symptoms, where a person may feel tired, usually sick and may have a fever. Signs and symptoms of acute inflammation may last for a few days.

Also Read: Autoimmune Disease: Learn What It Is About

Chronic Inflammation

Chronic inflammation may extend for months or years and it either has or may have an association to several diseases such as:

Diabetes

Cardiovascular disease

Arthritis and other joint diseases

Allergies

Chronic Obstructive Pulmonary Disease

Psoriasis

Rheumatoid arthritis

The symptoms of chronic inflammation will depend on the type of associated diseases but may also include generalised fatigue and pain.

Causes

Inflammation occurs when a physical factor stimulates an immune reaction. Inflammation does not really mean that there is an infection, however, an infection can cause inflammation.

Acute inflammation can result from:

Exposure to a bee sting, dust, or other substance

An injury

An infection

When the body identifies a pathogen, the immune system triggers several reactions:

The tissues start accumulating plasma proteins, leading to fluid build-up that results in swelling.

The system releases neutrophils, a type of white blood cell, which travel toward the affected area. These white blood cells contain molecules that combat pathogens.

Signs and Symptoms

Generally, signs of acute inflammation appear within hours or days, depending on the cause and how they develop and how long they last will also depend on the cause, which part of the body they affect and individual factors.

Some factors that can lead to acute inflammation include:

Acute bronchitis, appendicitis and other illness ending with itis

An ingrown toenail

A sore throat from a cold or flu

Wound

Chronic inflammation can develop if a person has:

Sensitivity: Hypersensitivity to an external trigger that may result in an allergic reaction.

Exposure: Long-term exposure or low-level exposure to an irritant like an industrial chemical can result in chronic inflammation.

Autoimmune disorders: The immune system mistakenly attacks normal healthy cells.

Continuous acute inflammation: In rare cases, a person may not get completely recovered from acute inflammation and this can lead to chronic inflammation.

Factors that may elevate the risk of chronic inflammation include:

Ageing

Obesity

Poor diet

Smoking

Low sex hormone levels

Improper sleep

Long-term health conditions that doctors associate with inflammation include:

Asthma

Chronic peptic ulcer

Tuberculosis

Rheumatoid arthritis

Periodontitis

Ulcerative colitis and Crohn’s disease

Sinusitis

Active hepatitis

Diagnosing Inflammation

When an inflammation is active in the human body, there will be a higher level of elements circulating in the blood known as biomarkers. One such biomarker is C- reactive protein (CRP). The healthcare provider may assess CRP levels to diagnose any inflammation in the body. Generally, CRP levels tend to be elevated in elderly people and those with comorbid disease conditions like cancer and obesity.

Also Read: Anti-Inflammatory Diet: Benefits, Foods To Eat And Avoid

Treatment

Generally, treatment for inflammation depends on the cause and severity. In most cases, acute inflammation may not need any treatment. However, sometimes not treating inflammation may result in life-threatening symptoms.

Acute Inflammation

The doctor may prescribe medications to remove the cause of inflammation, manage symptoms or both. For bacterial or fungal infection -antibiotics or antifungal medications are prescribed.

Nonsteroidal anti-inflammatory drugs are prescribed that may help relieve pain, swelling, fever and other symptoms, but will not remove the cause of inflammation. A person should only use these medications for a specific duration as suggested by the doctor, as they can result in adverse effects.

Pain relievers help to ease the pain but do not lessen inflammation.

Corticosteroids are prescribed to manage several conditions, including:

Arthritis

Temporal arteritis

Dermatitis

Inflammatory Bowel Disease

Systemic lupus

Hepatitis

Asthma

Allergic Reactions

Chronic Inflammation

Further, treatment for diseases that involve long-term or chronic inflammation will depend on the condition. Some drugs may work to curb the body’s immune reactions. These can help alleviate symptoms of rheumatoid arthritis, psoriasis, and other similar autoimmune reactions. However, they can also make a person less able to combat an infection if it occurs. People who had undergone transplant surgery need to take immunosuppressant drugs to avert the system from rejecting the new organs. They need to take extra care to avoid any exposure to infections.