INTRODUCTION ABOUT XYLOSON NASAL DROPS

XYLOSON NASAL DROPS is paediatric nasal drop used for symptomatic relief from nasal congestion in children. XYLOSON NASAL DROPS reduces nasal congestion, excessive nasal secretion and restores normal breathing. It contains a medicine called xylometazoline which works by thinning the mucus present in the nasal tract.

Always use XYLOSON NASAL DROPS as directed by your physician.One to two drops in each nostril, one or two times daily or as directed by the physician. It is for intranasal use only. Do not use XYLOSON NASAL DROPS for more than 7 days without consulting your doctor.

Before using XYLOSON NASAL DROPS inform your doctor if you have diabetes, hypertension, glaucoma, hyperthyroidism, or any heart problems. You must also inform your doctor if you have any other problems in nasal tract apart from nasal congestion such as chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis).

The most common side effects of using XYLOSON NASAL DROPS are irritation or burning sensation after application and nasal dryness. Consult your doctor if any of these side effect worsens.

USES OF XYLOSON NASAL DROPS

Nasal congestion

HOW XYLOSON NASAL DROPS WORKS

XYLOSON NASAL DROPS opens and clears the nasal passages. It works by narrowing down the blood vessels supplying the nasal passage. This helps swollen blood vessels of the nasal tract to return to its normal size which allows the air to pass through the nostrils more freely. It also reduces excessive nasal secretions and provides temporary relief from nasal inflammation, swelling and discomfort.

DIRECTIONS FOR USE

Always use XYLOSON NASAL DROPS as directed by your physician. It is for intranasal use only.

For Nasal Drops: Gently instill few drops of this medicine into each nostril. One to two drops in each nostril, one or two times daily or as directed by the physician.Clean the dropper after application.

For Nasal Spray: Insert the spray nozzle inside the affected nostril. Press the pump to release the spray and sniff at the same time. Repeat the same to the other nostril if required. Clean the nozzle after application.

To avoid possible spread of infection, this pack should only be used by a single person. Do not use XYLOSON NASAL DROPS for more than 7 days without consulting your doctor. Discard the unused portion after 28 days of opening it.

SIDE EFFECTS OF XYLOSON NASAL DROPS

COMMON

Dry nose
Nose discomfort
Headache
Nausea
Irritation or burning sensation after application

UNCOMMON

Nosebleeds

RARE

Stop using XYLOSON NASAL DROPS and contact your doctor immediately if you experience any of the following side effects:

Severe allergic reactions (such as swelling of the face, lips, tongue, and/or throat which can lead to difficulty in breathing or swallowing)
Severe itching of the skin, with a red rash or raised spots on the skin.

HOW TO MANAGE SIDE EFFECTS

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea And Vomiting

Take XYLOSON NASAL DROPS with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

WARNING & PRECAUTIONS

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any tools or machines if your ability is affected by XYLOSON NASAL DROPS.

ALLERGY

Contraindicated

Do not use XYLOSON NASAL DROPS if you are allergic to Xylometazoline or to any other ingredients of this medicine.

HEART DISEASE

Use with Caution

XYLOSON NASAL DROPS should be used with caution in patients with heart disease (such as hypertension, prolonged QT syndrome). Therefore, consult your doctor before using it.

USE IN PEDIATRICS

Consult your doctor

XYLOSON NASAL DROPS can be used in children and adolescents aged 12 years or above. You must consult your doctor before using XYLOSON NASAL DROPS if your child is aged 6 years or above. It is not recommended for use in children aged below 6 years. Therefore, consult your doctor for advice before administration

USE IN GERIATRICS

Use with Caution

XYLOSON NASAL DROPS should be used with caution in elderly patients. Therefore, consult your doctor for advice.

OTHERS

XYLOSON NASAL DROPS is not recommended for use if you:

Have had a recent neurosurgery
Have narrow-angle glaucoma (increased pressure within the eyes)
Have any problems in the nasal tract such as chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis)
Have an enlarged prostate gland
Have phaeochromocytoma (a rare tumour of the adrenal glands)

Before using XYLOSON NASAL DROPS, inform your doctor if you:

Have diabetes
Have hyperthyroidism (overactive thyroid gland)

INTERACTIONS

A. Drug-Drug interactions:

Antidepressants such as monoamine oxidase inhibitors (Ex. moclobemide, isocarboxazid, phenelzine and tranylcypromine), tricyclic antidepressants (Ex. amitriptyline, nortriptyline), lithium, fluoxetine, sertraline, citalopram, escitalopram etc
alpha-blockers (Ex. prazosin, terazocin) or beta blockers (Ex. propranolol, atenolol)
antiglaucoma (Ex. Timolol, betaxolol)

Overdosage:

If you or anyone else accidentally applied too much of XYLOSON NASAL DROPS, consult your doctor immediately.

SYNOPSIS

Drug	:	Xylometazoline
Pharmacological Category	:	Alpha-Adrenergic Agonist
Therapeutic Indication	:	Nasal congestion, sinusitis, perennial allergic rhinitis
Dosage Forms	:	Nasal Drops, Nasal Spray

MORE INFORMATION

STORAGE

Keep XYLOSON NASAL DROPS out of reach to children
Store XYLOSON NASAL DROPS at room temperature

FAQs ABOUT XYLOSON NASAL DROPS

Q: What is the use of XYLOSON NASAL DROPS ?

A: XYLOSON NASAL DROPS is used to relieve nasal congestion caused due to common cold, sinusitis or allergic rhinitis.

Q: Can XYLOSON NASAL DROPS be used every day?

A: Use XYLOSON NASAL DROPS for the duration prescribed by your doctor. Do not use XYLOSON NASAL DROPS for more than 7 days without consulting your doctor. Prolonged use of XYLOSON NASAL DROPS may worsen your condition.

Q: Is it safe to use XYLOSON NASAL DROPS ?

A: Yes. XYLOSON NASAL DROPS is one of the safe and well-tolerated medicine. It does not cause any harmful side effects. It may cause local irritation or burning sensation after application which is quite normal and disappears after a few minutes.

Q: What are the common side effects of XYLOSON NASAL DROPS ?

A: The most common side effects of using XYLOSON NASAL DROPS are irritation or burning sensation after application and nasal dryness. Consult your doctor if they bother you.

Q: Can XYLOSON NASAL DROPS be used in children?

A: XYLOSON NASAL DROPS can be used in children and adolescents aged 12 years or above. You must consult your doctor before using XYLOSON NASAL DROPS if your child is aged 6 years or above. It is not recommended for use in children aged below 6 years. Therefore, consult your doctor for advice before administration.

Q: Is XYLOSON NASAL DROPS an antihistamine?

A: XYLOSON NASAL DROPS is a sympathomimetic agonist which directly acts on the alpha-adrenergic receptors of the blood vessels supplying the nasal tract and narrows them down. This reduces swelling of the nasal tract and allows the air to pass through the nostrils more freely.

Q: How long it takes for XYLOSON NASAL DROPS to work?

A: XYLOSON NASAL DROPS may show its therapeutic effect after 5 to 10 minutes of application. It works by narrowing of blood vessels in the affected lining of the nose and helps to provide relief from congestion.

Q: Can XYLOSON NASAL DROPS cause rebound congestion?

A: Yes, XYLOSON NASAL DROPS may cause rebound congestion (worsening of congestion due to nasal decongestant sprays) if you use for more than the duration recommended by your doctor.

REFERENCES

1. K.D. Tripathi. Adrenergic System and Drugs. Essential of Medical Pharmacology. 7th Edition. Page – 136.

2. Xylometazoline. ScienceDirect.com. [Accessed on 8thJuly 2024]. https://www.sciencedirect.com/topics/medicine-and-dentistry/xylometazoline#:~:text=Clinical%20Pharmacology%3A,Therapeutic%20Effect%3A%20Decreased%20nasal%20congestion.

3. Ronald Eccles, Kaj Martensson and Shirley C. Chen. Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. Taylor Francis Online. January 2010. [Accessed on 8thJuly 2024]. https://www.tandfonline.com/doi/abs/10.1185/03007991003648015?journalCode=icmo20

4. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 8thJuly 2024]. https://www.medicines.org.uk/emc/files/pil.5984.pdf

5. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 8thJuly 2024]. https://www.medicines.org.uk/emc/files/pil.1412.pdf

AUTHOR DETAILS

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 12 Nov 2024 | 12:02 PM(IST)