INTRODUCTION ABOUT XYLOFLO NASAL DROPS

XYLOFLO NASAL DROPS is paediatric nasal drop used for symptomatic relief from nasal congestion in children. XYLOFLO NASAL DROPS reduces nasal congestion, excessive nasal secretion and restores normal breathing. It contains a medicine called xylometazoline which works by thinning the mucus present in the nasal tract.

Always use XYLOFLO NASAL DROPS as directed by your physician.One to two drops in each nostril, one or two times daily or as directed by the physician. It is for intranasal use only. Do not use XYLOFLO NASAL DROPS for more than 7 days without consulting your doctor.

Before using XYLOFLO NASAL DROPS inform your doctor if you have diabetes, hypertension, glaucoma, hyperthyroidism, or any heart problems. You must also inform your doctor if you have any other problems in nasal tract apart from nasal congestion such as chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis).

The most common side effects of using XYLOFLO NASAL DROPS are irritation or burning sensation after application and nasal dryness. Consult your doctor if any of these side effect worsens.

USES OF XYLOFLO NASAL DROPS

Nasal congestion

HOW XYLOFLO NASAL DROPS WORKS

XYLOFLO NASAL DROPS opens and clears the nasal passages. It works by narrowing down the blood vessels supplying the nasal passage. This helps swollen blood vessels of the nasal tract to return to its normal size which allows the air to pass through the nostrils more freely. It also reduces excessive nasal secretions and provides temporary relief from nasal inflammation, swelling and discomfort.

DIRECTIONS FOR USE

Always use XYLOFLO NASAL DROPS as directed by your physician. It is for intranasal use only.

For Nasal Drops: Gently instill few drops of this medicine into each nostril. One to two drops in each nostril, one or two times daily or as directed by the physician.Clean the dropper after application.

For Nasal Spray: Insert the spray nozzle inside the affected nostril. Press the pump to release the spray and sniff at the same time. Repeat the same to the other nostril if required. Clean the nozzle after application.

To avoid possible spread of infection, this pack should only be used by a single person. Do not use XYLOFLO NASAL DROPS for more than 7 days without consulting your doctor. Discard the unused portion after 28 days of opening it.

SIDE EFFECTS OF XYLOFLO NASAL DROPS

COMMON

Dry nose
Nose discomfort
Headache
Nausea
Irritation or burning sensation after application

UNCOMMON

Nosebleeds

RARE

Stop using XYLOFLO NASAL DROPS and contact your doctor immediately if you experience any of the following side effects:

Severe allergic reactions (such as swelling of the face, lips, tongue, and/or throat which can lead to difficulty in breathing or swallowing)
Severe itching of the skin, with a red rash or raised spots on the skin.

HOW TO MANAGE SIDE EFFECTS

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea And Vomiting

Take XYLOFLO NASAL DROPS with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

WARNING & PRECAUTIONS

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any tools or machines if your ability is affected by XYLOFLO NASAL DROPS.

ALLERGY

Contraindicated

Do not use XYLOFLO NASAL DROPS if you are allergic to Xylometazoline or to any other ingredients of this medicine.

HEART DISEASE

Use with Caution

XYLOFLO NASAL DROPS should be used with caution in patients with heart disease (such as hypertension, prolonged QT syndrome). Therefore, consult your doctor before using it.

USE IN PEDIATRICS

Consult your doctor

XYLOFLO NASAL DROPS can be used in children and adolescents aged 12 years or above. You must consult your doctor before using XYLOFLO NASAL DROPS if your child is aged 6 years or above. It is not recommended for use in children aged below 6 years. Therefore, consult your doctor for advice before administration

USE IN GERIATRICS

Use with Caution

XYLOFLO NASAL DROPS should be used with caution in elderly patients. Therefore, consult your doctor for advice.

OTHERS

XYLOFLO NASAL DROPS is not recommended for use if you:

Have had a recent neurosurgery
Have narrow-angle glaucoma (increased pressure within the eyes)
Have any problems in the nasal tract such as chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis)
Have an enlarged prostate gland
Have phaeochromocytoma (a rare tumour of the adrenal glands)

Before using XYLOFLO NASAL DROPS, inform your doctor if you:

Have diabetes
Have hyperthyroidism (overactive thyroid gland)

INTERACTIONS

A. Drug-Drug interactions:

Antidepressants such as monoamine oxidase inhibitors (Ex. moclobemide, isocarboxazid, phenelzine and tranylcypromine), tricyclic antidepressants (Ex. amitriptyline, nortriptyline), lithium, fluoxetine, sertraline, citalopram, escitalopram etc
alpha-blockers (Ex. prazosin, terazocin) or beta blockers (Ex. propranolol, atenolol)
antiglaucoma (Ex. Timolol, betaxolol)

Overdosage:

If you or anyone else accidentally applied too much of XYLOFLO NASAL DROPS, consult your doctor immediately.

SYNOPSIS

Drug	:	Xylometazoline
Pharmacological Category	:	Alpha-Adrenergic Agonist
Therapeutic Indication	:	Nasal congestion, sinusitis, perennial allergic rhinitis
Dosage Forms	:	Nasal Drops, Nasal Spray

MORE INFORMATION

STORAGE

Keep XYLOFLO NASAL DROPS out of reach to children
Store XYLOFLO NASAL DROPS at room temperature

FAQs ABOUT XYLOFLO NASAL DROPS

Q: What is the use of XYLOFLO NASAL DROPS ?

A: XYLOFLO NASAL DROPS is used to relieve nasal congestion caused due to common cold, sinusitis or allergic rhinitis.

Q: Can XYLOFLO NASAL DROPS be used every day?

A: Use XYLOFLO NASAL DROPS for the duration prescribed by your doctor. Do not use XYLOFLO NASAL DROPS for more than 7 days without consulting your doctor. Prolonged use of XYLOFLO NASAL DROPS may worsen your condition.

Q: Is it safe to use XYLOFLO NASAL DROPS ?

A: Yes. XYLOFLO NASAL DROPS is one of the safe and well-tolerated medicine. It does not cause any harmful side effects. It may cause local irritation or burning sensation after application which is quite normal and disappears after a few minutes.

Q: What are the common side effects of XYLOFLO NASAL DROPS ?

A: The most common side effects of using XYLOFLO NASAL DROPS are irritation or burning sensation after application and nasal dryness. Consult your doctor if they bother you.

Q: Can XYLOFLO NASAL DROPS be used in children?

A: XYLOFLO NASAL DROPS can be used in children and adolescents aged 12 years or above. You must consult your doctor before using XYLOFLO NASAL DROPS if your child is aged 6 years or above. It is not recommended for use in children aged below 6 years. Therefore, consult your doctor for advice before administration.

Q: Is XYLOFLO NASAL DROPS an antihistamine?

A: XYLOFLO NASAL DROPS is a sympathomimetic agonist which directly acts on the alpha-adrenergic receptors of the blood vessels supplying the nasal tract and narrows them down. This reduces swelling of the nasal tract and allows the air to pass through the nostrils more freely.

Q: How long it takes for XYLOFLO NASAL DROPS to work?

A: XYLOFLO NASAL DROPS may show its therapeutic effect after 5 to 10 minutes of application. It works by narrowing of blood vessels in the affected lining of the nose and helps to provide relief from congestion.

Q: Can XYLOFLO NASAL DROPS cause rebound congestion?

A: Yes, XYLOFLO NASAL DROPS may cause rebound congestion (worsening of congestion due to nasal decongestant sprays) if you use for more than the duration recommended by your doctor.

REFERENCES

1. K.D. Tripathi. Adrenergic System and Drugs. Essential of Medical Pharmacology. 7th Edition. Page – 136.

2. Xylometazoline. ScienceDirect.com. [Accessed on 8thJuly 2024]. https://www.sciencedirect.com/topics/medicine-and-dentistry/xylometazoline#:~:text=Clinical%20Pharmacology%3A,Therapeutic%20Effect%3A%20Decreased%20nasal%20congestion.

3. Ronald Eccles, Kaj Martensson and Shirley C. Chen. Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. Taylor Francis Online. January 2010. [Accessed on 8thJuly 2024]. https://www.tandfonline.com/doi/abs/10.1185/03007991003648015?journalCode=icmo20

4. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 8thJuly 2024]. https://www.medicines.org.uk/emc/files/pil.5984.pdf

5. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 8thJuly 2024]. https://www.medicines.org.uk/emc/files/pil.1412.pdf

AUTHOR DETAILS

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 12 Nov 2024 | 12:02 PM(IST)