INTRODUCTION ABOUT WIKORYL TABLET

WIKORYL TABLET is a combination of Chlorpheniramine, Paracetamol and Phenylephrine which belongs to the group of medicines called Antihistamines, Analgesics and Nasal decongestants respectively. It is used to relieve the symptoms of hay fever, common cold or other upper respiratory allergies, like headache, facial congestion and pressure, nasal congestion, runny nose, sneezing, minor aches and pains, itching of the nose, throat or eyes and watery eyes. It can also be used to clear nasal passages and decongest facial openings and passages.

Hay fever is a seasonal allergy that occurs in response to specific allergens like pollens, present at certain times of the year (spring or fall) and causes more short-term symptoms.

WIKORYL TABLET is not recommended for use in children and adolescents (aged less than 12 years). Consult your doctor before giving this medicine to your child.

Before taking WIKORYL TABLET, inform your doctor if you have any kidney, liver, heart, thyroid or lung problems, diabetes or glaucoma.

WIKORYL TABLET should be used with caution in pregnant and breastfeeding women, so consult your doctor before taking it.

The most common side effects of taking WIKORYL TABLET are dizziness, drowsiness, dry mouth, nose or throat, headache, nausea, nervousness and difficulty in sleeping. Contact your doctor if any of the above side effects worsen.

USES OF WIKORYL TABLET

It is used to:

  • relieve the symptoms of hay fever, common cold or other upper respiratory allergies
  • to clear nasal passages and decongest facial openings and passages

HOW WIKORYL TABLET WORKS

WIKORYL TABLET relieves upper respiratory symptoms where Chlorpheniramine binds to the histamine H1 receptor and blocks its action, resulting in temporary relief of the negative symptoms (runny nose, sneezing, watery and itchy eyes) brought on by histamine, where Paracetamol relieves pain by elevation of the pain threshold and reduces fever by acting on the on the heat-regulating centre in your brain and Phenylephrine constricts blood vessels and reduces the blood flow to certain areas, thus decreasing swelling and allowing nasal and respiratory passages to open up.

DIRECTIONS FOR USE

Take WIKORYL TABLET as advised by your physician. It can be taken with or without food.

For Tablet, Capsule: Swallow WIKORYL TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.

SIDE EFFECTS OF WIKORYL TABLET

COMMON

  • dizziness, drowsiness
  • nausea
  • dry mouth, nose or throat
  • headache
  • nervousness
  • difficulty in sleeping

RARE

Stop taking WIKORYL TABLET and contact your doctor immediately if you experience any of the following side effects:

  • severe allergic reactions (rash, itching, chest tightness, trouble breathing, swollen mouth, face, lips or tongue)
  • chest pain, high blood pressure, fast heartbeat
  • dark urine, pale faeces, yellow skin or eyes
  • trouble urinating
  • hallucinations, severe nervousness, shaking
  • stomach pain, unusual tiredness
  • redness or swelling
  • severe throat pain accompanied or followed by fever, headache, rash, nausea or vomiting

HOW TO MANAGE SIDE EFFECTS

Nausea:

Take WIKORYL TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Headache:

Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache.

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. Consult your doctor if stomach pain doesn't improve.

WARNING & PRECAUTIONS

PREGNANCY

WIKORYL TABLET should be used with caution in pregnant women. Consult your doctor before taking it.

BREASTFEEDING

WIKORYL TABLET should be used with caution in breastfeeding women. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or use any machines if you feel drowsy or dizzy after taking WIKORYL TABLET.

ALCOHOL

Avoid consumption of alcohol with WIKORYL TABLET as it may affect you more than usual. WIKORYL TABLET should be used with caution in patients with alcohol dependence.

KIDNEY

WIKORYL TABLET should be used with caution in patients having kidney problems, trouble urinating or urinary blockage. Consult your doctor before taking it.

LIVER

WIKORYL TABLET should be used with caution in patients with liver problems and viral hepatitis. Consult your doctor before taking it.

ALLERGY

Do not take WIKORYL TABLET if you are allergic to Chlorpheniramine, Paracetamol, Phenylephrine or any other ingredients of this medicine.

LUNGS

WIKORYL TABLET is not recommended for use in patients with breathing problems like emphysema or chronic bronchitis. WIKORYL TABLET should be used with caution in patients with other breathing problems like asthma. Consult your doctor before taking it.

HEART DISEASE

WIKORYL TABLET is not recommended in patients with heart disease or high blood pressure. WIKORYL TABLET should be used with caution in patients with other heart diseases. Consult your doctor before taking it.

OTHERS

WIKORYL TABLET is not recommended for use if you:

  • have diabetes
  • have a condition in which there is increased pressure inside your eye
  • have an enlarged prostate gland
  • have problems with your adrenal gland
  • have trouble sleeping
  • have stomach problems

Before taking WIKORYL TABLET, inform your doctor if you:

  • have an overactive thyroid gland

Use in pediatrics:

WIKORYL TABLET is not recommended for use in children (aged less than 2 years). Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking it.

Use in geriatrics:

WIKORYL TABLET should be used with caution in elderly patients as they may be more sensitive to its effect. Consult your doctor before taking it.

INTERACTIONS

A. Drug - Drug interactions:

Before taking WIKORYL TABLET, inform your doctor if you are taking any of the following medicine:

  • medicines used to manage depression (Ex. isocarboxazid, phenelzine, tranylcypromine)
  • other medicines containing paracetamol
  • medicines used to induce sleep or manage anxiety (Ex. zolpidem, diazepam, alprazolam)
  • warfarin (use for blood clot)
  • medicines used to manage fits (Ex. carbamazepine, phenytoin)
  • medicines used to relax muscles (Ex. carisoprodol, cyclobenzaprine)

Overdosage:

If you or anyone else accidentally took too much of WIKORYL TABLET, contact your doctor immediately. Symptoms of overdose are liver damage.

SYNOPSIS

Drug :   Chlorpheniramine, Paracetamol, Phenylephrine
Pharmacological Category :   Antihistamine, Antipyretic-Analgesic, Nasal decongestant
Therapeutic Indication :   Rhinorrhea, congestion, common cold and fever
Dosage Forms :   Tablet, Syrup, Suspension, Liquid, Drops, Oral drops, Syrup

MORE INFORMATION

  • Keep WIKORYL TABLET out of reach of children
  • Store at room temperature below 25°C

FAQs ABOUT WIKORYL TABLET

Can WIKORYL TABLET be used on infants?

WIKORYL TABLET is not recommended for use in children (aged less than 2 years). Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking it.

What if I forget to take a dose of WIKORYL TABLET?

If you forget to take a dose of WIKORYL TABLET, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for a forgotten dose.

Can WIKORYL TABLET be crushed?

No. Do not break, crush or chew WIKORYL TABLET. Simply swallow it whole with a glass of water. Consult your doctor for advice.

Can I stop taking WIKORYL TABLET?

Do not stop taking WIKORYL TABLET without consulting your doctor. You can do it if you experience any serious side effects with your doctor’s consultation. If you have any more doubts regarding the use of this medicine, ask your doctor.

Can WIKORYL TABLET cause dizziness?

Dizziness is a common side effect of WIKORYL TABLET. In such case, lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest and drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol. Tell your doctor if your dizziness doesn’t improve.

What precautions do I need to follow while taking WIKORYL TABLET?

Patients taking WIKORYL TABLET must inform their doctor about their pre-existing disease conditions like kidney, liver, heart, thyroid or lung problems, diabetes or glaucoma. Contact your doctor if you have any unusual symptoms.

Can WIKORYL TABLET be taken in pregnancy?

WIKORYL TABLET should be used with caution in pregnancy as it is not known if it can harm the unborn baby. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before taking this medicine.

REFERENCES

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Allergic Rhinitis. Pharmacotherapy Handbook. Ninth edition. Page- 813.

2. Kiran, M., Vakharia, M., Pawaskar, L., & Sheikh, S. Efficacy and safety of a fixed dose combination of paracetamol, chlorpheniramine maleate and phenylephrine in management of common cold: a phase IV, open-labelled, multi-centric study. International Journal of Basic & Clinical Pharmacology. 2018. [Accessed on 21st June 2022] https://www.ijbcp.com/index.php/ijbcp/article/view/3076

3. PubChem Compound Summary for CID 2725, Chlorpheniramine. National Center for Biotechnology Information. June 2022. [Accessed on 21st June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Chlorpheniramine#section=Mechanism-of-Action

4. Arpimed. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 21st June 2022] https://arpimed.am/anti-cold-tablets/

5. Dailymed. Chlorpheniramine + Paracetamol + Phenylephrine. [Revised in November 2021] [Accessed on 21st June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=97097bfc-880a-42f9-b4c6-ed3e0be880d7

6. Laboratorios Cinfa, S.A. Chlorpheniramine + Paracetamol + Phenylephrine. [Revised in February 2017] [Accessed on 21st June 2022] https://www.cinfainternational.com/wp-content/uploads/PIL_Pharmagrip-capsules_HK.pdf

7. Devlife Corporation Pvt. Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 21st June 2022] https://www.dlc.net.in/paracetamol-phenylephrine-hydrochloride-chlorpheniramine-maleate-tablets-5757725.html

8. Milan Laboratories (India) Pvt. Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Revised in January 2019] [Accessed on 21st June 2022] https://exphar.com/wp-content/uploads/2021/02/Febrilex-Leaflet-EN.pdf

9. Pharmactive Ilac San.ve Tic. A.S. Chlorpheniramine + Paracetamol + Phenylephrine. [Revised in September 2019] [Accessed on 21st June 2022] https://pharmactive.com.tr/img/files/pdf-en/kt/Teragrip_650_mg10_mg4_mg_film_kapli_tablet_KT-en.pdf

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 21 Nov 2022 | 05:23 PM(IST)

Happy Customers 9M+ Happy Customers
Authentic Products 100% Authentic
Best Quality Quality Checked Products
    Net Qty
    1 N
    Shelf Life
    720 Days
    Item Weight
    17.5 g
    Ingredient
    Chlorpheniramine 2 mg+Paracetamol 500 mg+Phenylephrine 5 mg
    Hsn Code
    30049099
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