INTRODUCTION ABOUT SMUTH CREAM

SMUTH CREAM is a combination of Calcium Dobesilate, Hydrocortisone Acetate, Lignocaine and Zinc Oxide which belong to the group of medicines called Anti-haemorrhoids. It is used to manage haemorrhoids or piles (lumps inside or around your anus) and anal fissures (a small tear in the lining of anus) and constipation.

SMUTH CREAM is not recommended for use if you have tuberculous or fungal lesions or skin vaccinia (viral infection), varicella (chicken pox) and acute herpes simplex infection. Consult with your doctor before using it.

SMUTH CREAM should be used with caution in patients with lung, liver and heart problems. SMUTH CREAM should be used during pregnancy only if clearly necessary. It should be used with caution in breastfeeding women. Consult your doctor before using it.

SMUTH CREAM is not recommended for use in children under 12 years of age. It should be used with caution in elderly patients. The most common side effects of using SMUTH CREAM are burning, irritation, redness, itchiness at the application site. Consult your doctor if any of the symptoms worsen.

USES OF SMUTH CREAM

Manage:

Haemorrhoids
Anal fissures
Constipation

HOW SMUTH CREAM WORKS

Calcium Dobesilate is a vasoprotective medicine that works by strengthening the blood vessels at the affected site and also promote fast healing. Lignocaine is a local anaesthetic blocks the transmission of pain signals from nerves to brain and Hydrocortisone belongs to the class of steroids works by decreasing itching, inflammation, redness and swelling. Zinc oxide is an astringent, which helps to reduce painful swelling and shrink the haemorrhoids. It also protects the skin on the anus from infections. Thus SMUTH CREAM helps to shrink pile mass and heals anal fissure effectively.

DIRECTIONS FOR USE

Apply SMUTH CREAM as advised by your physician. It is for topical use only. Wash your hands before and after use. Apply a thin layer of this medicine over the affected area with the help of an applicator or as directed by physician. Avoid the medicine in contact with your eyes, ears, nose or mouth. If accidental exposure occurs, wash your eyes with water and seek immediate medical attention.

SIDE EFFECTS OF SMUTH CREAM

COMMON

burning, irritation, itching and redness at the site of application

RARE

Stop using SMUTH CREAM and contact your doctor immediately if you experience any of the following side effects:

increased redness and irritation
signs and symptoms of methemoglobinemia characterized by pale, grey or blue coloured skin (cyanosis), headache, fits, rapid heart rate, shortness of breath, light-headedness or fatigue

WARNING & PRECAUTIONS

PREGNANCY

Monitoring required

SMUTH CREAM should be used during pregnancy only if clearly necessary. Consult your doctor before using it.

BREASTFEEDING

Use with Caution

SMUTH CREAM should be used with caution in breastfeeding women. Consult your doctor before using it.

LIVER

Use with Caution

SMUTH CREAM should be used with caution in patients with liver problems. Consult with your doctor before using it.

ALLERGY

Contraindicated

Do not use SMUTH CREAM if you are allergic to Calcium Dobesilate, Hydrocortisone Acetate, Lignocaine, Zinc Oxide or any other ingredient of this medicine.

LUNGS

Use with Caution

SMUTH CREAM should be used with caution in patients with lung problems. Consult with your doctor before using it.

HEART DISEASE

Use with Caution

SMUTH CREAM should be used with caution in patients with severe shock and heart block. Consult with your doctor before using it.

OTHERS

SMUTH CREAM is not recommended for use if you have:

tuberculous or fungal lesions or skin vaccinia (viral infection)
varicella (chicken pox)
acute herpes simplex infection

Before using SMUTH CREAM inform your doctor if you have:

glucose-6- phosphate dehydrogenase deficiency (a genetic disorder that affects red blood cells)
methemoglobinemia (blood disorder)

Use in Pediatrics:

SMUTH CREAM is not recommended for use in children under 12 years of age. Consult your doctor before using it.

Use in Geriatrics:

SMUTH CREAM should be used with caution in elderly patients. Consult your doctor before using it.

INTERACTIONS

A. Drug-Drug Interactions:

Before using SMUTH CREAM, inform your doctor if you are using any of the following medicine:

medicine used to manage chest pain, high blood pressure (Ex. nitroglycerin, nitroprusside, nitric oxide, nitrous oxide)
anaesthetics (medicines used to produce temporary loss of consciousness (Ex. benzocaine, lidocaine, bupivacaine, mepivacaine)
medicine used for cancer (Ex. cyclophosphamide, flutamide, rasburicase, ifosfamide, hydroxyurea)
antibiotics (medicine used to manage infections) (Ex. dapsone, sulfonamides, nitrofurantoin, para-aminosalicylic acid)
medicine used to manage malaria (Ex. quinine, chloroquine, primaquine)
medicine used to manage fits (Ex. phenytoin, sodium valproate, phenobarbital)
acetaminophen (used to manage pain and fever)
metoclopramide (used to manage nausea and vomiting)
sulfasalazine (used to manage ulcerative colitis and Chron’s disease)
oral laxatives (used to manage constipation) (Ex. lactulose)
antiarrhythmics (used to manage irregular heartbeats) (Ex. quinidine)

Overdosage:

If you or anyone else accidentally ingested or used too much of SMUTH CREAM, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug	:	Calcium Dobesilate, Hydrocortisone Acetate, Lignocaine and Zinc Oxide
Pharmacological Category	:	Vaso protectives, Corticosteroids, Local Anaesthetics and Astringent
Therapeutic Indication	:	Haemorrhoids, Anal fissures and Constipation
Dosage Forms	:	Cream

MORE INFORMATION

Keep SMUTH CREAM out of reach of children
Store SMUTH CREAM below 25°C

FAQs ABOUT SMUTH CREAM

Q: Is SMUTH CREAM safe to use?

A: Yes. SMUTH CREAM is well-tolerated, with a consistent safety profile and provides an efficient fast and safe symptomatic relief from haemorrhoids or piles, anal fissures, bleeding with pain and itching. It also helps to promote easy evacuation of stools. Consult your doctor before using it.

Q: What lifestyle modifications have to be taken while using SMUTH CREAM?

A: Take bath with warm water while using this medicine. This will soothe the area and will also aid in pain. Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain bread and cereals to help in digestion and ensure speedy recovery. Make sure to avoid spicy, oil-rich food and drink at least 6-8 glasses of water daily and exercise regularly to maintain healthy bowel movement.

Q: How to use SMUTH CREAM?

A: Apply SMUTH CREAM as advised by your physician. It is for topical use only. Wash your hands before and after use. Apply a thin layer of this medicine over the affected area with the help of an applicator or as directed by physician. Avoid the medicine in contact with your eyes, ears, nose or mouth. If accidental exposure occurs, wash your eyes with water and seek immediate medical attention.

Q: Can I stop using SMUTH CREAM when my symptoms are relieved?

A: No, do not stop using SMUTH CREAM and complete the full course of management. Your symptoms may improve before the condition is completely cured. Consult your doctor before stop using the medicine. Otherwise, it may lead to worsening of the condition.

Q: Is SMUTH CREAM safe to use in pregnant women?

A: SMUTH CREAM should be used during pregnancy only if clearly necessary. Inform your doctor if you are pregnant or planning for pregnancy before using this medicine.

Q: Will SMUTH CREAM be more effective if can I use more than prescribed?

A: No, higher than the recommended dosage of SMUTH CREAM will not be more effective. Moreover, it can result in too much of medicine being absorbed into the body and cause unwanted side effects. If you are experiencing increased severity of your symptoms, consult your doctor for re-evaluation.

Q: How does SMUTH CREAM work?

A: SMUTH CREAM works on the walls of the small blood vessels and reduces their leakage and fragility.

Q: What are the disadvantages of SMUTH CREAM?

A: SMUTH CREAM has some side effects such as site irritation, itching, burning sensation and changes in skin colour. Inform your physician if its persists or worsens.

REFERENCES

K.D. Tripathi. Drugs Acting on Skin and Mucous Membranes, Local Anaesthetics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895, 887, 360.

2. Bethesda (MD). Calcium Dobesilate. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 30th August 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Calcium%20Dobesilate

3. Bethesda (MD). Hydrocortisone. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 30th August 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Hydrocortisone

4. Bethesda (MD). Lignocaine. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 30th August 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Lignocaine

5. Bethesda (MD). Zinc Oxide. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 30th August 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Zinc%20Oxide

6. The Boots Company. Electronic Medicines Compendium (EMC). [Revised in July 2016] [Accessed on 30th August 2022]. https://www.medicines.org.uk/emc/files/pil.6730.pdf

7. Lidocaine and Hydrocortisone Cream. Daily Med: National Library of Medicine: National Institute of Health. [Revised in February 2022] [Accessed on 30th August 2022]. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5c57a310-8d46-4862-bf2a-a7e4fd5bee57

8. Hydrocortisone Ointment. Daily Med: National Library of Medicine: National Institute of Health. [Revised in January 2022] [Accessed on 30th August 2022]. https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=7ba59aa6-b828-4048-bf86-90c90d9894a0&type=pdf

9. Lidocaine Ointment. Daily Med: National Library of Medicine: National Institute of Health. [Revised in May 2018] [Accessed on 30th August 2022]. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=12639881-632d-445d-9ff5-b84567f49179

10. Calcium Dobesilate, Lignocaine, Hydrocortisone Acetate, Zinc oxide Cream. MK Medicine. [Accessed on 30th August 2022]. https://www.mkmedicine.in/calcium-dobesilate-0.25-lignocaine-3-hydrocortisone-acetate-0.25-zinc-5.html

11. SWIFT CREAM (Calcium Dobesilate, Lignocaine, Hydrocortisone Acetate, Zinc oxide). Invision Medi Sciences Pvt. Ltd. [Accessed on 30th August 2022]. http://www.invisionmedi.com/category/swift-cream.htm

12. Pilesrin Cream (Calcium Dobesilate, Lignocaine, Hydrocortisone Acetate, Zinc oxide). Orion Life science Ltd. [Accessed on 30th August 2022]. https://www.orionlifes.com/product/calcium-dobesilatehydrocortisone-lignocaine-zinc-cream/

13. Doberest (Calcium Dobesilate, Lignocaine, Hydrocortisone Acetate, Zinc oxide). Arlak Biotech Pvt. Ltd. [Accessed on 30th August 2022]. https://www.arlakbiotech.com/products-offering/calcium-dobesilate-lignocalne-hydrocortisonezinc-cream/

AUTHOR DETAILS

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 01 Mar 2024 | 02:53 PM(IST)