SITASON D 100/10 TABLET is a combination of Dapagliflozin and Sitagliptin which belongs to the group of medicines called Antidiabetic agents. It is used in adults to manage type II diabetes mellitus which is inadequately controlled on metformin monotherapy. Type 2 diabetes is a condition in which your body does not make enough insulin and the insulin that is produced does not work as well as it should. This results in sugar (glucose) build-up in the blood and thus high blood sugar levels.
SITASON D 100/10 TABLET is not recommended for use in patients having severe kidney problems or those on dialysis. Before taking SITASON D 100/10 TABLET, inform your doctor if you have inflammation of the pancreas, gallstones, alcohol dependence, or very high levels of triglycerides (a form of fat) in the blood or any heart, kidney or liver problems. SITASON D 100/10 TABLET should be used in pregnant women only if considered clearly necessary. SITASON D 100/10 TABLET should be used with caution in breastfeeding women. Safety and effectiveness of SITASON D 100/10 TABLET in children and adolescents (under 18 years of age) have not been established.
It is important to stay on the diet and exercise recommended by your doctor while taking SITASON D 100/10 TABLET as it can help your body use its blood sugar better. The most common side effects of taking SITASON D 100/10 TABLET are nausea, headache, flatulence and constipation. Consult your doctor if any of the side effects worsen or persist for a long period of time.
SITASON D 100/10 TABLET effectively controls blood sugar levels where dapagliflozin inhibits SGLT2, increasing urinary glucose excretion and reducing blood levels of glucose and sitagliptin inhibits DPP-4, increases glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), resulting in increased insulin synthesis and decreased glucagon release.
Take SITASON D 100/10 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. SITASON D 100/10 TABLET can be taken with or without food. Your doctor will decide the correct dose and duration of SITASON D 100/10 TABLET therapy depending on your age, body weight and disease condition.
Stop taking SITASON D 100/10 TABLET and contact your physician immediately if you experience any of the following side effects:
Eat plenty of fiber-rich foods such as fresh fruits, vegetables, cereals and drink plenty of water. Exercise more regularly. If symptom persists, consult your doctor.
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Rest and relax. Keep yourself hydrated by drinking more fluids like water. Applying a pain-relieving balm on the forehead can be beneficial. Avoid consumption of alcohol, as it could aggravate your headache. If symptom persists, consult your doctor.
Take SITASON D 100/10 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating oil rich or spicy food. If symptom persists, consult your doctor.
SITASON D 100/10 TABLET can be used in pregnant women only if considered clearly necessary. Consult your doctor before taking it.
SITASON D 100/10 TABLET can be used with caution in breastfeeding women. Consult your doctor before taking it.
Do not drive or operate any machines if you feel dizzy or sleepy after taking SITASON D 100/10 TABLET.
Avoid consumption of alcohol while taking SITASON D 100/10 TABLET as it may increase the chance of diabetic ketoacidosis. Consult your doctor for advice.
SITASON D 100/10 TABLET can be used with caution in patients who had or have any kidney problems. Consult your doctor before taking SITASON D 100/10 TABLET.
SITASON D 100/10 TABLET can be used with caution in patients with severe liver impairment. Consult your doctor before taking SITASON D 100/10 TABLET.
Do not take SITASON D 100/10 TABLET if you are allergic to Dapagliflozin, Sitagliptin or any other ingredients of this medicine.
SITASON D 100/10 TABLET can be used with caution in patients who ever had heart failure. Consult your doctor before taking SITASON D 100/10 TABLET.
Safety and effectiveness of SITASON D 100/10 TABLET in children and adolescents (under 18 years of age) have not been established. Consult your child’s doctor for advice.
No dose adjustment of SITASON D 100/10 TABLET is required for elderly patients, however, consult your doctor before taking it.
SITASON D 100/10 TABLET is not recommended for use if you have:
Before taking SITASON D 100/10 TABLET inform your doctor if you:
A. Drug-Drug interactions:
Before taking SITASON D 100/10 TABLET, inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally take too much of SITASON D 100/10 TABLET, consult your doctor or visit a nearby hospital immediately.
Drug | : | Dapagliflozin, Sitagliptin |
Pharmacological Category | : | Sodium-Glucose Cotransporter 2 (SGLT2) inhibitor, Dipeptidyl Peptidase 4 (DPP-4) inhibitor |
Therapeutic Indication | : | Type II diabetes mellitus |
Dosage Forms | : | Tablet |
A: SITASON D 100/10 TABLET is a combination of Dapagliflozin and Sitagliptin which belongs to the group of medicines called Antidiabetic agents. It is used in adults to manage type II diabetes mellitus which is inadequately controlled on metformin monotherapy.
A: Yes, SITASON D 100/10 TABLET may cause weight loss in some individuals. To avoid weight loss, follow a healthy diet and regular physical activity as advised by your physician. However, if the weight loss bothers you, consult your doctor.
A: Taking SITASON D 100/10 TABLET along with insulin might increase the chance of hypoglycemia (decreased blood sugar levels). Consult your doctor before taking any other medicine with SITASON D 100/10 TABLET.
A: SITASON D 100/10 TABLET effectively controls blood sugar levels where dapagliflozin inhibits SGLT2, increasing urinary glucose excretion and reducing blood levels of glucose and sitagliptin inhibits DPP-4, increases glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), resulting in increased insulin synthesis and decreased glucagon release.
A: SITASON D 100/10 TABLET can be used with caution in patients who had or have any kidney problems. Your doctor may monitor your kidney function test before and during management with this medicine to manage the risk of any unusual effects. Consult your doctor before taking SITASON D 100/10 TABLET.
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3. Annaswamy Raji, Zhi Jin Xu, Raymond L. H. Lam, Edward A.O’Neill, Keith D. Kaufman, Samuel S. Engel. Efficacy and Safety of Sitagliptin Compared with Dapagliflozin in People ≥65 Years Old with Type 2 Diabetes and Mild Renal Insufficiency. SpringerLink. August 2020. [Accessed on 27th November 2023] https://link.springer.com/article/10.1007/s13300-020-00907-w
4. Torrent Pharmaceuticals Ltd. Sitaxa D/ Sitalix D/Glucreta S (Dapagliflozin + Sitagliptin). [Revised in July 2022] [Accessed on 27th November 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/3096.pdf
5. Cipla Ltd. Exemed Pharmaceuticals. Darasach S (Dapagliflozin + Sitagliptin). Ciplamed. [Revised in September 2022] [Accessed on 27th November 2023] https://www.ciplamed.com/content/dapasach-s-tablets
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