INTRODUCTION ABOUT ITRAL EYE OINTMENT

ITRAL EYE OINTMENT contains Itraconazole which belongs to the group of medicines called Antifungals. It is used to manage fungal eye infections which includes fungal keratitis/mycotic corneal ulcer (corneal infection), fungal conjunctivitis (fungal infection of conjunctiva) and keratomycosis (invasive corneal infection of eye).

Fungal eye infection is a condition that affects the deeper layers of the cornea or leads to formation of scar that affects the vision which is generally characterized by symptoms such as eye pain, eye redness, blurred vision or sensitivity to light.       

ITRAL EYE OINTMENT is not recommended for use in patients who are allergic to itraconazole. Before using ITRAL EYE OINTMENT, inform your doctor if you have any pre-existing diseases or scheduled for any upcoming surgery.

ITRAL EYE OINTMENT should be used with caution in pregnant and breastfeeding women. Consult your doctor before using the medicine.

If you experience any side effects or unusual effects during management with this medicine, consult your doctor immediately.

USES OF ITRAL EYE OINTMENT

• Manage fungal eye infections which include fungal keratitis/mycotic corneal ulcer (corneal infection), fungal conjunctivitis (fungal infection of conjunctiva) and keratomycosis (invasive corneal infection of eye)

HOW ITRAL EYE OINTMENT WORKS

ITRAL EYE OINTMENT works by inhibiting ergosterol synthesis (an organic compound responsible for maintaining cell membrane integrity of fungi cell) that leads to fungal cell membrane abnormalities (marked with increased permeability and disruption of fungi cell) thus causing destruction to the fungi cell and managing the occurrence of fungal infections in affected individuals.  

DIRECTIONS FOR USE

Use ITRAL EYE OINTMENT as advised by your physician. It is for ophthalmic use only. Wash your hands well before using the eye ointment. Tilt your head back a little and pull the lower lid of your eye to form a small pocket. Hold the tube upside down near to the eye. Apply enough pressure to the tube to release a thin line of ointment along the inside of the lower eyelid and do not touch your eyes. Close the eye for a moment or two and then blink a few times to spread the ointment around the inside of your eye and to get clear vision.

Your doctor will decide the correct dose, frequency and duration of ITRAL EYE OINTMENT for you depending upon your age and type or severity of the infection.

WARNING & PRECAUTIONS

PREGNANCY

ITRAL EYE OINTMENT should be used with caution in pregnant women. Consult your doctor before using the medicine.   

BREASTFEEDING

ITRAL EYE OINTMENT should be used with caution in breastfeeding women. Consult your doctor before using the medicine. 

ALLERGY

Do not use ITRAL EYE OINTMENT if you are allergic to itraconazole or any other ingredients of this medicine.    

INTERACTIONS

A. Drug–drug interactions:

Before using ITRAL EYE OINTMENT, inform your doctor, if you are taking or using any medicines including prescription, non-prescription medicines, herbals or vitamin supplements.

Overdosage:

If you or anyone else accidentally use too much of ITRAL EYE OINTMENT, consult your doctor or visit the nearby hospital.     

SYNOPSIS

MORE INFORMATION

• Keep ITRAL EYE OINTMENT out of reach of children
• Store it below 30ºC

FAQs ABOUT ITRAL EYE OINTMENT

What is ITRAL EYE OINTMENT used for?

ITRAL EYE OINTMENT is used to manage fungal eye infections which includes fungal keratitis/mycotic corneal ulcer (corneal infection), fungal conjunctivitis (fungal infection of conjunctiva) and keratomycosis (invasive corneal infection of eye).

How does ITRAL EYE OINTMENT work?

ITRAL EYE OINTMENT works by inhibiting ergosterol synthesis (an organic compound responsible for maintaining cell membrane integrity of fungi cell) that leads to fungal cell membrane abnormalities (marked with increased permeability and disruption of fungi cell) thus causing destruction to the fungi cell and managing the occurrence of fungal infections in affected individuals.

How to use ITRAL EYE OINTMENT?

Use ITRAL EYE OINTMENT as advised by your physician. It is for ophthalmic use only. Wash your hands well before using the eye ointment. Tilt your head back a little and pull the lower lid of your eye to form a small pocket. Hold the tube upside down near to the eye. Apply enough pressure to the tube to release a thin line of ointment along the inside of the lower eyelid and do not touch your eyes. Close the eye for a moment or two and then blink a few times to spread the ointment around the inside of your eye and to get clear vision. 

Can I use any other medicines along with ITRAL EYE OINTMENT?

Before using ITRAL EYE OINTMENT, inform your doctor, if you are taking or using any medicines including prescription, non-prescription medicines, herbals or vitamin supplements to manage the risk of drug interactions which can lead to unusual effects or serious effects.

Can ITRAL EYE OINTMENT be used in pregnant women?

ITRAL EYE OINTMENT should be used with caution in pregnant women. Consult your doctor for advice before using the medicine if you are pregnant or planning to get pregnant.

REFERENCES

1. K.D. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page 794.

2. Heidi Kurn; Roopma Wadhwa. Itraconazole. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. April 2022. [Accessed on 30th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK557874/

3. Bethesda. Itraconazole. NIH National Library of Medicine. National Center for Biotechnology Information. September 2022. [Accessed on 30th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK500573/

4. Aditya K Gupta, Elizabeth A Cooper, Gabriele Ginter. Efficacy and safety of itraconazole use in children. NIH National Library of Medicine. National Center for Biotechnology Information. July 2003. [Accessed on 30th September 2022] https://pubmed.ncbi.nlm.nih.gov/12956205/

5. Jawa pharmaceuticals Pvt Ltd. Itral Eye Drops. [Accessed on 30th September 2022] https://www.jawapharma.com/manufacturer%20and%20supplier%20of%20antifungal.html

AUTHOR DETAILS

Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 03 Oct 2022 | 05:36 PM(IST)