INTRODUCTION ABOUT FINE NERVE CAPSULE
FINE NERVE CAPSULE is a combination of Pregabalin, Alpha Lipoic Acid, Mecobalamin (Methylcobalamin), L Methylfolate Calcium, and Pyridoxal 5 Phosphate which belongs to the group of medicines called Anticonvulsants, Antioxidants, and Vitamins, respectively. It is used to manage neuropathic pain (damage/injury to the nerves) in affected individuals.
FINE NERVE CAPSULE is not recommended for use in patients allergic to Pregabalin, and/or any other ingredients of this medicine. It is also not recommended for use in patients suffering from drug abuse/dependence.
Before taking FINE NERVE CAPSULE, inform your doctor if you have a history of heart disease, and/or suffering from diabetes, lung problems (such as respiratory disorders), liver problems (such as serious liver disease), and kidney problems (such as serious kidney disease).
FINE NERVE CAPSULE is not recommended for use in pregnant and breastfeeding women. It is also not recommended for use in children and adolescents (aged below 18 years) and advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor.
The most common side effects of taking FINE NERVE CAPSULE are dizziness, drowsiness, headache, increased appetite, elation, confusion, disorientation, and/or decrease in sexual interest. Consult your doctor if any of these symptoms worsens.
USES OF FINE NERVE CAPSULE
- Manage neuropathic pain in affected individuals
HOW FINE NERVE CAPSULE WORKS
FINE NERVE CAPSULE provides relief from neuropathic pain, where pregabalin blocks pain sensation (due to neuropathic pain) by interfering with the pain signals originating from the damaged nerves, alpha lipoic acid reduces neuropathic pain/stress by inhibiting oxidative stress and improving microvascular circulation, and mecobalamin, l methylfolate calcium & pyridoxal 5 phosphate improves cutaneous sensibility and reduces pain (due to neuropathic stress) by increasing nitric oxide synthesis and blood flow to the peripheral nerves thus providing relief from neuropathic pain in affected individuals.
DIRECTIONS FOR USE
Take FINE NERVE CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF FINE NERVE CAPSULE
COMMON
- dizziness
- drowsiness
- headache
- increased appetite
- elation, confusion, disorientation, decrease in sexual interest, irritability
- disturbance in attention, clumsiness, memory impairment, loss of memory, shaking of the body parts, difficulty in speaking, tingling, numbness, sedation, lethargy, sleeplessness, weakness, feeling abnormal
- double vision, blurred vision
- sensation of spinning, problems with balance, falls
- dry mouth, constipation, vomiting, flatulence. Diarrhoea, nausea, swollen abdomen
- difficulties with erection
- swelling of the body including extremities
- feeling drunk, abnormal style of walking
- weight gain
- muscle cramp, joint pain, back pain, pain in limb
- sore throat
UNCOMMON
- loss of appetite
- weight loss
- low blood sugar
- high blood sugar
- change in perception of self
- restlessness
- depression
- agitation
- mood swings
- difficulty finding words
- hallucinations
- abnormal dreams
- panic attack
- lack of interest
- aggression
- elevated mood
- mental impairment
- difficulty with thinking
- increase in sexual interest
- sexual problems such as inability to get sexual climax
- delayed ejaculation
- changes in eyesight
- unusual eye movement
- changes in vision including tunnel vision
- flashes of light
- jerky movements
- reduced reflexes
- increased activity
- dizziness on standing
- sensitive skin
- loss of taste
- burning sensation
- tremor on movement
- decreased consciousness
- loss of consciousness
- fainting
- increased sensitivity to noise
- feeling unwell
- dry eyes
- eye swelling
- eye pain
- weak eyes
- watery eyes
- eye irritation
- heart rhythm disturbances, increased heart rate, low blood pressure, high blood pressure, changes in heartbeat, heart failure
- flushing, hot flushes
- difficulty in breathing, dry nose, nasal congestion
- increased saliva production, heartburn, numbness around mouth
- sweating, rashes, chills, fever
- muscle twitching, joint swelling, muscle stiffness, pain including muscle pain, neck pain
- breast pain
- difficulty while urinating, painful urination, urinary incontinence
- weakness, thirst, chest tightness
- signs of hypersensitivity reactions (immune mediated response to an allergen) such as swollen face, itchiness, hives, runny nose, nosebleed, cough, and snoring
- painful menstrual periods
- coldness of hands and feet
RARE
- abnormal sense of smell
- swinging vision
- altered perception of depth
- visual brightness
- vision loss
- dilated pupils
- cross eyes
- cold sweat
- tightness of the throat
- swollen tongue
- inflammation of the pancreas
- difficulty in swallowing
- decreased or slow body movements
- difficulty with writing properly
- increased fluid in the abdomen
- fluid in the lungs
- convulsions
- heart rhythm disturbances
- muscle damage
- breast discharge
- abnormal breast growth
- breast growth in males
- interrupted menstrual periods
- kidney failure
- reduced urine volume
- urinary retention
- decrease in white blood cell count
- inappropriate behaviour
- signs of allergic reactions such as shortness of breath
- keratitis (inflammation of the eyes)
- signs of a serious skin reaction such as rash, blisters, peeling skin, and pain
- jaundice (yellowish skin and eyes)
- Parkinsonism (symptoms resembling Parkinson’s disease such as tremors, decreased ability to move, and rigidity)
Stop taking FINE NERVE CAPSULE and contact your doctor if you experience any of the following side effects:
- signs of allergic reactions such as swelling of face/lips/tongue/throat and/or skin rash
- redness in skin, blisters, or peeling of skin
- blurring/loss of vision, temporary changes in eyesight
- suicidal thoughts
- convulsion
HOW TO MANAGE SIDE EFFECTS
Dizziness
Lie down until the dizziness passes and get up slowly. Do not bend down suddenly. Get a lot of rest. Walk slowly and carefully. Take plenty of fluids. Avoid drinking coffee, alcohol, or smoking. Consult your doctor if the condition persists for long or gets worsened.
Headache
Take rest and plenty of water. Avoid taking alcohol and skipping meals. Do not strain your eyes by watching screen for long time. Consult your doctor if the condition persists for long or gets worsened.
Diarrhoea
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.
Constipation
Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.
Nausea and vomiting
Try to take FINE NERVE CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
WARNING & PRECAUTIONS
PREGNANCY
FINE NERVE CAPSULE is generally not recommended for use during pregnancy and in women planning for pregnancy unless it is clearly necessary. Effective contraception is recommended to be used by women of child-bearing potential while taking this medicine. Consult your doctor before taking the medicine.
BREASTFEEDING
FINE NERVE CAPSULE is not recommended to be used in breastfeeding women unless considered clearly necessary. Consult your doctor before taking the medicine.
DRIVING AND USING MACHINES
Do not drive or operate any machine while taking FINE NERVE CAPSULE since it may cause dizziness, sleepiness, and/or decreased concentration in an individual.
ALCOHOL
FINE NERVE CAPSULE is not recommended for use in patients with a history of alcohol abuse. Avoid consumption of alcohol while taking FINE NERVE CAPSULE since it may alter the effect of the medicine.
KIDNEY
FINE NERVE CAPSULE should be used with caution in patients with serious kidney diseases or renal impairment. Consult your doctor for advice before taking the medicine.
LIVER
FINE NERVE CAPSULE should be used with caution in patients with serious liver diseases. Consult your doctor before taking the medicine.
ALLERGY
Do not take FINE NERVE CAPSULE if you are allergic to pregabalin or any other ingredients of this medicine. Consult your doctor before taking the medicine.
LUNGS
FINE NERVE CAPSULE should be used with caution in patients with lung problems such as respiratory disorders. Consult your doctor before taking the medicine.
HEART DISEASE
FINE NERVE CAPSULE should be used with caution in patients with history of heart diseases. Consult your doctor for advice before taking the medicine.
OTHERS
FINE NERVE CAPSULE is not recommended for use if you:
- have drug abuse/dependence
Before taking FINE NERVE CAPSULE, inform your doctor if you:
- have diabetes
Use in Paediatrics
FINE NERVE CAPSULE is not recommended to be used in children and adolescents (below 18 years). Consult your doctor before taking the medicine.
Use in Geriatrics
FINE NERVE CAPSULE should be used with caution in elderly patients (aged 65 years and above) except in patients having kidney problems. Consult your doctor before taking the medicine.
INTERACTIONS
A. Drug-Drug Interactions
Before taking FINE NERVE CAPSULE, inform your doctor, if you are taking any of the following medicine:
- oxycodone (medicine used to manage pain and inflammation)
- lorazepam (medicine used to manage anxiety)
- opioids (medicines used to manage pain) Ex. morphine
- antiepileptic drugs (medicines used to manage epilepsy) Ex. sodium valproate, carbamazepine, lamotrigine.
Overdosage:
If you or anyone else accidentally takes too much of FINE NERVE CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are sleepiness, confusion, agitation, and/or restlessness.
SYNOPSIS
| Drug | : | Pregabalin, Alpha Lipoic Acid, Mecobalamin (Methylcobalamin), L Methylfolate Calcium, and Pyridoxal 5 Phosphate |
| Pharmacological Category | : | Anticonvulsants, Antioxidants, and Vitamins |
| Therapeutic Indication | : | Neuropathic pain |
| Dosage Forms | : | Capsule |
MORE INFORMATION
- Keep the medicine out of reach in children
- Store FINE NERVE CAPSULE below 30°C
FAQs ABOUT FINE NERVE CAPSULE
What FINE NERVE CAPSULE is used for?
FINE NERVE CAPSULE is used to manage neuropathic pain in affected individuals which is a condition that occurs due to damage/injury to the nerves that transfer information between brain and spinal cord from skin, muscles, and/or other parts of the body. It is generally characterized by symptoms such as numbness/prickling/tingling sensation in feet/hands, extreme sensitivity to touch, and/or sharp throbbing pain in affected individuals.
What side effects are seen with FINE NERVE CAPSULE?
The most common side effects associated with the use of FINE NERVE CAPSULE are dizziness, drowsiness, headache, increased appetite, elation, confusion, disorientation, and/or decrease in sexual interest. Consult your doctor if any of these symptoms worsens.
Who should avoid taking FINE NERVE CAPSULE?
FINE NERVE CAPSULE is not recommended for use in patients allergic to pregabalin, and/or any other ingredients of this medicine. It is also not recommended for use in patients with drug dependence/abuse. The medicine is also not recommended for use in pregnant and breastfeeding women (unless considered clearly necessary) which is also not recommended to be used in children and adolescents (aged below 18 years). Consult your doctor before taking the medicines.
Is FINE NERVE CAPSULE safe to be used in children and elderly patients?
No, FINE NERVE CAPSULE is not recommended for use in children and adolescents (aged below 18 years) which should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.
How FINE NERVE CAPSULE works?
FINE NERVE CAPSULE provides relief from neuropathic pain, where pregabalin blocks pain sensation (due to neuropathic pain) by interfering with the pain signals originating from the damaged nerves, alpha lipoic acid reduces neuropathic pain/stress by inhibiting oxidative stress and improving microvascular circulation, and mecobalamin, l methylfolate calcium & pyridoxal 5 phosphate improves cutaneous sensibility and reduces pain (due to neuropathic stress) by increasing nitric oxide synthesis and blood flow to the peripheral nerves thus providing relief from neuropathic pain in affected individuals.
What is method of taking FINE NERVE CAPSULE?
Take FINE NERVE CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Is FINE NERVE CAPSULE safe to use in pregnant women?
No, FINE NERVE CAPSULE is generally not recommended for use during pregnancy and in women planning for pregnancy unless it is considered clearly necessary. Effective contraception is recommended to be used by women of child-bearing potential while taking this medicine to avoid undesirable harm to the foetus. Consult your doctor before taking the medicines.
What if I forget to take FINE NERVE CAPSULE dose?
If you forgot to take FINE NERVE CAPSULE dose, take it as early as possible. Do not double the up to make up for the missed dosage. Consult your doctor before taking the medicine.
When to stop taking FINE NERVE CAPSULE?
Do not stop taking FINE NERVE CAPSULE unless your doctor advice you to do so. Your management will be stopped gradually over a minimum of 1 week.
REFERENCES
1. Loretta Vileikyte, Andrew JM Boulton.Management of Neuropathic Pain. Managing Neuropathic Pain in the Diabetic Patient. Second edition. 2012. Page – 39.
2. V. Seshiah. Diabetic Neuropathy. Microvascular Complications of Diabetes. Edition: 2009. Page – 22
3. George Kukurin DC DACAN. Section II: The neurobiology of alternative therapy for the treatment of peripheral neuropathy. Integrative Neurology: Hope and Help for People Suffering from Peripheral Neuropathy. Edition: 2009. Page – 92
4. Jorge R. Miranda-Massari, Michael J. Gonzalez,Francisco J. Jimenez, Myriam Z. Allende-Vigo, and Jorge Duconge. Metabolic Correction in the Management of Diabetic Peripheral Neuropathy: Improving Clinical Results Beyond Symptom Control. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. June 2013. [Accessed on 16th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682498/
5. Vivek Verma, Nirmal Singh, and Amteshwar Singh Jaggi.Pregabalin in Neuropathic Pain: Evidence and Possible Mechanisms. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. January 2014. [Accessed on 16th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915349/
6. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 16th September 2022] https://www.medicines.org.uk/emc/files/pil.7057.pdf
7. Akumentis Healthcare. Fine Nerve Capsule. [Accessed on 16th September 2022] https://akumentishealthcare.com/ortho/
USEFUL DIAGNOSTIC TESTS
- Nerve Conduction test
AUTHOR DETAILS
