BRAINGATES NERVE CAPSULE is used for the management of neuropathic pain. It is a combination of Pregabalin and Methylcobalamin which belongs to the group of medicines called Anticonvulsants and Vitamin-B complex respectively. It consists of Methylcobalamin and Pregabalin where Methylcobalamin acts by rejuvenating the damaged neurons by improving the production of myelin and pregabalin acts by interfering with various pain signals travelling through the damaged nerves and the brain, thus leading to a significant pain relief in various neuropathic pain states.
Do not stop taking BRAINGATES NERVE CAPSULE without consulting your doctor as it could precipitate withdrawal symptoms such as headache, insomnia, nausea, pain, diarrhea, flu syndrome, anxiety, nervousness, depression, convulsion, excessive sweating, dizziness and physical dependence. BRAINGATES NERVE CAPSULE has high potential to cause addiction and therefore caution should be exercised among patients who already has a history of substance abuse.
BRAINGATES NERVE CAPSULE is not recommended for use in pregnant or breastfeeding women unless advised by the doctor and in male patients who plan to father a child. The most common side effects are dizziness, sleepiness, headache, dry mouth, mood changes, fluid retention and weight gain. Consult your doctor if any of the side effects worsen.
BRAINGATES NERVE CAPSULE effectively alleviates the symptoms of various types of neuropathic pain, where Methylcobalamin acts by rejuvenating the damaged neurons by improving the production of myelin and Pregabalin acts by interfering with various pain signals travelling through the damaged nerves and the brain, thus leading to a significant pain relief in various neuropathic pain states.
Stop taking BRAINGATES NERVE CAPSULE and contact your doctor immediately if you experience any of the following side effects:
There is no proper information on the use of BRAINGATES NERVE CAPSULE during pregnancy and therefore should be used only if the benefit to the mother clearly outweighs the potential risk to the fetus.
BRAINGATES NERVE CAPSULE is not recommended for use in breastfeeding women unless it is considered clearly necessary.
Do not drive or operate any heavy tools or machines if you experience dizziness or sleepiness after taking this medicine.
Avoid consumption of alcohol while taking BRAINGATES NERVE CAPSULE, as it may cause impairment of motor skills and sedating effects of alcohol.
BRAINGATES NERVE CAPSULE should be taken with caution in patients with impaired kidney function.
BRAINGATES NERVE CAPSULE should be taken with caution in patients with liver disease.
Do not take BRAINGATES NERVE CAPSULE if you are allergic to Pregabalin, Methylcobalamin or any other ingredients of this medicine.
BRAINGATES NERVE CAPSULE should be taken with caution in patients with heart disease such as congestive heart failure.
BRAINGATES NERVE CAPSULE is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data.
BRAINGATES NERVE CAPSULE should be used with caution in elderly patients (aged 65 years and above), especially in patients with decreased renal function. Proper dose adjustments and careful monitoring of kidney function are required in such patients.
BRAINGATES NERVE CAPSULE is not recommended for use if you:
Before taking this medicine, inform your physician if you:
A. Drug-Drug interactions:
Before taking the medicine, inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally takes too much of BRAINGATES NERVE CAPSULE, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms such as sleepiness, confusion, agitation, restlessness or seizures.
Drug | : | Pregabalin, Methylcobalamin |
Pharmacological Category | : | Anticonvulsants, Vitamin B complex |
Therapeutic Indication | : | Neuropathic pain |
Dosage Forms | : | Tablet, Capsule, Soft gels, Syrup |
Disease Description
Neuropathic pain is now defined by the International Association for the Study of Pain (IASP) as ‘pain caused by a lesion or disease of the somatosensory nervous system’. It is the result of disease or damage anywhere along the neuraxis of the peripheral or central (spinal and supraspinal) nervous system.
Hear what our expert say about handling nerve pain:
A: Fertility studies in men have shown that there were no effects on sperm motility. However, BRAINGATES NERVE CAPSULE can be associated with an increased risk of male-mediated teratogenicity (abnormalities in fetus). Men being managed with this medicine who plan to father a child should be informed about the potential risk of male-mediated teratogenicity. There are not enough clinical data on the effects of this medicine on female fertility.
A: Yes. It may cause weight gain in some individuals mainly due to the formation of peripheral edema (fluid retention). Inform your doctor if you have diabetes prior to management with [as a precaution.
A: Yes, BRAINGATES NERVE CAPSULE may cause decrease in sex drive (libido) in some individuals, although not everybody gets them.
A: Yes, BRAINGATES NERVE CAPSULE has high potential to create substance abuse or dependence and therefore caution should be exercised among patients who already has a history of substance abuse.
A: No. Do not stop taking BRAINGATES NERVE CAPSULE without consulting your doctor as it could precipitate withdrawal symptoms such as headache, lack of sleep, nausea, pain, diarrhea, flu syndrome, anxiety, nervousness, depression, convulsion, hyperhidrosis and dizziness and dependence. If your condition improves, contact your doctor so that he might reduce the dose appropriately before discontinuation of the therapy with the medicine.
1. KD. Tripathi. Antiepileptic Drugs & Hematinics and Erythropoietin. Essentials of medical pharmacology. Seventh edition. 2013. Page-420 & 608.
2. Gerald G. Briggs and Roger K. Freeman. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page-3223-3225.
3. Yasmin U Dongre and Onkar C Swami. Sustained release pregabalin with Methylcobalamin in neuropathic pain: an Indian real-life experience. NCBI; PMC US National Library of Medicine, National Institute of Health. May 2013. [Accessed on 21st October 2022] click here
4. Gupta JK and Qureshi Shaiba Sana. Potential Benefits of Methylcobalamin: A Review. Austin Potential benefits of Pharmacology and Therapeutics. 2015. [Accessed on 21st October 2022] click here
5. Ram Prabhoo, Atul Panghate, Raj Pavitra Dewda, Balaji More, Tanay Prabhoo and Rajiv Rana. Efficacy and Tolerability of a Fixed Dose Combination of Methylcobalamin and Pregabalin in the Management of Painful Neuropathy. NCBI; PMC US National Library of Medicine, National Institute of Health. November 2012. [Accessed on 21st October 2022] click here
6. Torrent Pharmaceuticals Ltd. Predgeb M OD (Pregabalin Sustained Release and Methylcobalamin Tablets). Torrentian.com. May 2017. [Accessed on 21st October 2022] click here
7. Torrent Pharmaceuticals Ltd. Pregalin M. (Pregabalin & Methylcobalamin Capsules). Torrentian.com. May 2017. [Accessed on 21st October 2022] click here
8. Cipla Ltd. Nova M Capsules (Pregabalin + Methylcobalamin). Ciplamed.com. [Revised in May 2016]. [Accessed on 21st October 2022] click here
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