INTRODUCTION ABOUT AMAZEO OD 100MG TABLET

AMAZEO OD 100MG TABLET is used to manage schizophrenia in affected individuals. It contains Amisulpride which belongs to the group of medicines called Antipsychotics. It works by blocking dopamine D2 receptors (proteins responsible for synthesis and release of dopamine) in brain which results in reduced synthesis of dopamine thus improving thoughts, feelings and behaviour and thereby managing symptoms of schizophrenia in affected individuals.

AMAZEO OD 100MG TABLET is not recommended for use in patients with breast cancer or prolactin dependent tumor, phaeochromocytoma (type of adrenal gland tumor), and/or pituitary tumor. It is also not recommended for use in patients allergic to Amisulpride or any other ingredients of this medicine. Before taking the medicine, inform your doctor if you have diabetes, Parkinson’s disease (type of brain disorder), fits, signs of low potassium levels in blood (such as constipation, fatigue, muscle damage), stroke, kidney problems, and/or liver problems (such as hepatic impairment).

AMAZEO OD 100MG TABLET is not recommended for use during pregnancy and in women planning for pregnancy. It is also not recommended for use in breast feeding women. It is not recommended for use in children and adolescents (below 18 years of age) which should be used with caution in elderly patients (aged above 65 years). The most common side effects are feeling anxious, drowsy or agitated, constipation, nausea, vomiting, and/or blurred vision. Consult your doctor if any of these symptoms worsens.

USES OF AMAZEO OD 100MG TABLET

Used to manage schizophrenia

HOW AMAZEO OD 100MG TABLET WORKS

AMAZEO OD 100MG TABLET works by blocking dopamine D2 receptors (proteins responsible for synthesis and release of dopamine) in brain which results in reduced synthesis of dopamine thus improving thoughts, feelings and behaviour and thereby managing symptoms of schizophrenia in affected individuals.

DIRECTIONS FOR USE

Take AMAZEO OD 100MG TABLET as advised by your physician
For Tablet: Swallow the medicine with a glass of water. Do not crush or chew the medicine
For Orally Disintegrating Tablet: Place AMAZEO OD 100MG TABLET inside your mouth and allow it to dissolve completely
Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition

SIDE EFFECTS OF AMAZEO OD 100MG TABLET

Common side effects of AMAZEO OD 100MG TABLET:

difficulty sleeping, feeling anxious, agitated
feeling drowsy/sleepy
constipation, nausea, vomiting, dry mouth
weight gain
unusual production of breast milk in women and men, breast pain
absence of menstrual period
breast enlargement (in men)
difficulty in getting/maintaining an erection, and/or ejaculating
dizziness (due to low blood pressure)
blurred vision
high blood sugar

increase in blood pressure
difficulty passing urine

Stop taking AMAZEO OD 100MG TABLET and contact your doctor immediately if you experience any of the following side effects:

signs of an allergic reaction symptoms such as difficulty in swallowing/breathing (due to swelling of the hands, feet, ankles, face, lips or throat), itchy, lumpy rash, and/or nettle rash
fits or seizures
signs of neuroleptic malignant syndrome such as high temperature, sweating, stiff muscles, fast heartbeat, fast breathing, feel confused, drowsy, and/or agitated
signs of blood clots in the veins (especially in the legs) such as swelling, pain, and/or redness in the leg which may travel through blood vessels to lungs causing chest pain and difficulty in breathing
fatigue, loss of appetite, nausea, vomiting, abdominal pain and/or yellow discolouration of the eyes or skin

AMAZEO OD 100MG TABLET should be used with caution in elderly patients (aged above 65 years).

OTHERS

It is not recommended for use if you have:

breast cancer or prolactin dependent tumour
tumour on adrenal gland (phaeochromocytoma)
pituitary tumour

Before taking the medicine, inform your doctor if you have:

diabetes
Parkinson’s disease (type of brain disorder)
Fits or seizures
signs of low potassium levels in blood such as constipation, fatigue, muscle damage
stroke
history of blood clots
agranulocytosis (condition marked by low number of white blood cells)
signs of leukopenia (low white blood cell count)

INTERACTIONS

A. Drug-Drug interactions:

Before taking AMAZEO OD 100MG TABLET, inform your doctor, if you are taking any of the following medicine.

CNS agents (Ex. Levodopa)
Dopamine agonists (Ex. ropinirole and bromocriptine)
class IA antiarrhythmic agents (Ex. quinidine, disopyramide, sotalol, amiodarone)
atypical antipsychotics (Ex. clozapine)
Antipsychotic agents (Ex. risperidone, quetiapine, olanzapine)
Antihypertensives (Ex. clonidine, diltiazem, verapamil, guanfacine, digitalis)
Anti-malarial agents (Ex. mefloquine)
Barbiturates
Benzodiazepines (Ex. diazepam, lorazepam)
Opiate (narcotic) analgesics (Ex. tramadol, indomethacin)
Antihistamines (Ex. promethazine)
Diuretics (Ex. bumetanide, ethacrynic acid, furosemide)
Laxatives (Ex. bisacodyl)
Glucocorticoids (Ex. prednisone, prednisolone, triamcinolone)

Overdosage:

If you or anyone else accidentally take too much of AMAZEO OD 100MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling restless or shaky, rigid muscles, feeling drowsy and/or sleepy which could lead to a loss of consciousness.

SYNOPSIS

Drug	:	Amisulpride
Pharmacological Category	:	Antipsychotic agents
Therapeutic Indication	:	Schizophrenia
Dosage Forms	:	Tablet

MORE INFORMATION

FAQs ABOUT AMAZEO OD 100MG TABLET

Q: What AMAZEO OD 100MG TABLET is used for?

A: It is used in the management of schizophrenia which is a serious mental disorder that affects a person’s ability to think, feel and/or behave clearly. It is generally characterized by symptoms such as delusions, hallucinations, and/or confused thoughts in affected individuals.

Q: How AMAZEO OD 100MG TABLET is taken?

A: Take AMAZEO OD 100MG TABLET as advised by your physician. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Q: Can AMAZEO OD 100MG TABLET be stopped without consulting the doctor?

A: No. It should not be stopped without consulting a doctor since it may cause withdrawal symptoms such as muscle stiffness, and/or unusual body movements.

Q: How AMAZEO OD 100MG TABLET WORKS?

A: AMAZEO OD 100MG TABLET works by blocking dopamine D2 receptors (proteins responsible for synthesis and release of dopamine) in brain which results in reduced synthesis of dopamine thus improving thoughts, feelings and behaviour and thereby managing symptoms of schizophrenia in affected individuals.

Q: Can AMAZEO OD 100MG TABLET be used during pregnancy?

A: No. It should not be used during pregnancy or in women planning for pregnancy since it may affect the fetus.

REFERENCES

1. K.D. Tripathi. Drugs Used in Mental Illness: Antipsychotic and Antimanic Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 443.

2. M P Curran,C M Perry. Amisulpride: a review of its use in the management of schizophrenia. NIH National Library of Medicine. National Center for Biotechnology Information. [Revised in 2001] [Accessed 25th April 2022] click here

3. Diogo Telles-Correia, António Barbosa, Helena Cortez-Pinto, Carlos Campos, Nuno B F Rocha, and Sérgio Machado. Psychotropic drugs and liver disease: A critical review of pharmacokinetics and liver toxicity. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2017] [Accessed 25th April 2022] click here

4. AMISYT – 25. East West Pharma India Pvt. Ltd. [Accessed on 25th April 2022] click here

5. SOLTUS-300. Intas Pharmaceuticals Ltd. [Accessed on 25th April 2022] click here

6. Delpharm Dijon. Electronic Medicines Compendium (EMC). [Revised in February 2021] [Accessed on 25th April 2022] click here

AUTHOR DETAILS

Written By Dr. Janet.C - Pharm.D

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 15 Nov 2024 | 03:48 PM(IST)