INTRODUCTION ABOUT ADDPHOS GRANULES
ADDPHOS GRANULES contains Sodium acid phosphate which belongs to the group of medicines called Inorganic salts. It is used to manage hypophosphatemia (low blood phosphorous levels) and hypercalcemia (high blood calcium levels). It can also be used to manage phosphate depletion and calcium-based kidney stone.
ADDPHOS GRANULES should be used with caution in patients with impaired kidney function, congestive heart failure or high blood pressure. The safety of ADDPHOS GRANULES in pregnant and breastfeeding women has not been established. Consult your doctor before taking it.
ADDPHOS GRANULES should be used with caution in elderly patients. Consult your doctor before taking it. Inform your doctor if you experience any side effects after taking ADDPHOS GRANULES.
USES OF ADDPHOS GRANULES
To manage:
- Hypophosphatemia
- Hypercalcemia
- Phosphate depletion
- Calcium based kidney stone
HOW ADDPHOS GRANULES WORKS
ADDPHOS GRANULES work by decreasing calcium in blood in patients with hypercalcemia. It also works by binding to the calcium ions present in the gut and helps to manage kidney stones and the oral phosphate present in this medicine helps to correct hypophosphatemia (low blood phosphate levels).
DIRECTIONS FOR USE
Take ADDPHOS GRANULES as advised by your physician. It should be taken with meals. This medicine should be emptied and dissolved in 2/3rd to 1 full glass of water. Stir briskly and swallow the contents immediately. Your doctor will decide the correct dose and duration for you based upon your age, body weight and disease condition.
WARNING & PRECAUTIONS
PREGNANCY
The safety of ADDPHOS GRANULES in pregnant women has not been established. However, ADDPHOS GRANULES should be used with caution in pregnant women having high blood pressure (pre-eclamptic toxemia). Consult your doctor before taking it.
BREASTFEEDING
The safety of ADDPHOS GRANULES in breastfeeding women has not been established. Consult your doctor before taking it.
KIDNEY
ADDPHOS GRANULES should be taken with caution in patients with impaired kidney function. Consult your doctor before taking it.
ALLERGY
Do not take ADDPHOS GRANULES if you are allergic to Sodium acid phosphate or any of the other ingredients of this medicine.
HEART DISEASE
ADDPHOS GRANULES should be taken with caution in patients undergoing management for congestive heart failure or high blood pressure. Consult your doctor before taking it.
OTHERS
Before taking ADDPHOS GRANULES, inform your doctor if you:
- have any conditions associated with significant electrolyte imbalance
Use in Geriatrics:
ADDPHOS GRANULES should be used with caution in elderly patients due to risk of hypocalcemia (low blood calcium levels). Consult your doctor before taking it.
INTERACTIONS
A. Drug - Drug interactions:
Before taking ADDPHOS GRANULES, inform your doctor if you are taking any of the following medicines:
- medicines used to reduce acidity (Ex. aluminium hydroxide, calcium carbonate, magnesium carbonate)
- calcium supplements
- vitamin D (used to maintain bone health)
- parathyroid hormone (used to control blood calcium levels)
- anticonvulsants (used to manage fits) Ex. phenobarbital, carbamazepine
- bile Acid Sequestrants (used to lower cholesterol) Ex. cholestyramine
- corticosteroids (used to manage inflammatory conditions) Ex. prednisone or methyl prednisone
- insulin (used to manage diabetes mellitus)
- ACE inhibitors (used to manage high blood pressure) Ex. benazepril, captopril, enalapril and lisinopril
- cyclosporine (used to manage rejection of organ transplantation)
- heparin (used to thin blood)
- Non-steroidal Anti-Inflammatory drugs (used to manage pain) Ex. ibuprofen
- cardiac Glycosides (used for heart failure) Ex. digoxin
Overdosage:
If you or anyone else accidentally take too much of ADDPHOS GRANULES, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include low blood calcium levels.
SYNOPSIS
| Drug | : | Sodium acid phosphate |
| Pharmacological Category | : | Alkali metal phosphates |
| Therapeutic Indication | : | Hypophosphatemia, Hypercalcemia, Phosphate depletion, Calcium based kidney stone |
| Dosage Forms | : | Granules |
MORE INFORMATION
- Keep ADDPHOS GRANULES out of reach of children
- Store ADDPHOS GRANULES below 30°C
FAQs ABOUT ADDPHOS GRANULES
Q: Can ADDPHOS GRANULES be taken with food?
A: Take ADDPHOS GRANULES as advised by your physician. It should be taken with meals. This medicine should be emptied and dissolved in 2/3rd to 1 full glass of water. Stir briskly and swallow the contents immediately. Your doctor will decide the correct dose and duration for you based upon your age, body weight and disease condition.
Q: What precautions must be taken while using ADDPHOS GRANULES?
A: Considerations should be given to the sodium and potassium content of ADDPHOS GRANULES before administration to patients suffering from conditions associated with significant electrolyte imbalance or impaired kidney function. ADDPHOS GRANULES is also used with caution in patients with restricted sodium intake is indicated, Ex. in the management of congestive cardiac failure, high blood pressure. Contact your doctor before taking it.
Q: What does ADDPHOS GRANULES do to the body?
A: ADDPHOS GRANULES work by decreasing calcium in blood in patients with hypercalcemia. It also works by binding to the calcium ions present in the gut and helps to manage kidney stones and the oral phosphate present in this medicine helps to correct hypophosphatemia (low blood phosphate levels).
Q: Can ADDPHOS GRANULES be stopped?
A: Do not stop using ADDPHOS GRANULES until your doctor tells you to stop. If you experience any unwanted effects, worsening of your condition or any new symptoms. Contact your doctor in such case.
Q: Is ADDPHOS GRANULES safe in pregnancy?
A: The safety of ADDPHOS GRANULES in pregnant women has not been established. However, ADDPHOS GRANULES should be used with caution in pregnant women having high blood pressure (pre-eclamptic toxemia). Consult your doctor before taking it.
REFERENCES
1. Sean C Sweetman. Electrolytes. Martindale The Complete Drug Reference. 36th edition. 2009. Page- 1682.
2. Johnson, Mark & Hillier, Keith. Sodium Acid Phosphate. ResearchGate. January 2011. [Accessed on 17th August 2022] https://www.researchgate.net/publication/288473589_Sodium_Acid_Phosphate
3. Bethesda (MD). Monosodium phosphate. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Monosodium-phosphate
4. AddPhos (Sodium acid phosphate granules). Steadfast Medishield. [Accessed on 17th August 2022] https://www.steadfast.co.in/addphos/
USEFUL DIAGNOSTIC TESTS
- Serum phosphorous
- Serum calcium
- Serum sodium
AUTHOR DETAILS
