INTRODUCTION

NICOTEX NICOTINE contains Nicotine which is used to help people stop smoking. It relieves nicotine withdrawal symptoms and cravings when you stop smoking or temporarily reduce smoking in order to facilitate smoking cessation. It is a trans-dermal/skin patch developed using the principle of Nicotine Replacement Therapy (NRT) that helps you quit smoking. This patch when placed on your body gradually releases nicotine throughout the day. It gradually decreases the nicotine intake over 12 weeks (the step-down dosing approach), helping you to quit smoking.

Apply one patch a day to the area that is comfortable and suitable throughout the day. Use as instructed by your physician. It is not recommended for children and adolescents under 18 years of age. Tell your doctor before using this patch if you are suffering from any heart, liver or kidney disease. You must not smoke while using this patch as it can result in dangerous effects.

USES OF NICOTEX NICOTINE

Used to help people stop smoking
Relieves or prevent withdrawal symptoms of smoking

HOW NICOTEX NICOTINE WORKS

NICOTEX NICOTINE works on the step-down dosing approach that gradually decreases the nicotine intake over 12 weeks, helping you to quit smoking.

DIRECTIONS FOR USE

Apply one patch a day to the area that is comfortable and suitable throughout the day. Use as instructed by your physician. Check the label before use.

SIDE EFFECTS OF NICOTEX NICOTINE

COMMON

dizziness
mouth sore
nausea
sore throat
vomiting

RARE

skin redness (caused by the patch), swelling or rash
irregular heartbeat or palpitations

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea) or indigestion:

Stick to simple meals and do not eat rich or spicy foods.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Mouth sore:

Avoid spicy and sour foods until the ulcers heal. Drink plenty of fluids and rinse your mouth regularly with warm, slightly salted water.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

WARNING & PRECAUTIONS

PREGNANCY

NICOTEX NICOTINE should be used with caution in pregnant women. Consult your doctor before taking this medicine.

BREASTFEEDING

NICOTEX NICOTINE is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

KIDNEY

NICOTEX NICOTINE should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER

NICOTEX NICOTINE should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY

Do not take NICOTEX NICOTINE if you are allergic (hypersensitive) to Nicotine, adhesive tape or any of the ingredients in this patch.

HEART DISEASE

NICOTEX NICOTINE should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.

OTHERS

Tell your doctor if you had or have a condition such as:

uncontrolled blood pressure
stomach ulcers
diabetes
seizures

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

theophylline (used to manage asthma)
non-nicotine stop smoking drug
tacrine (used for Alzheimer’s disease)
clozapine (used for schizophrenia)
ropinirole (used to manage Parkinson’s disease)

SYNOPSIS

Drug	:	Nicotine
Pharmacological Category	:	Smoking Cessation Aid
Therapeutic Indication	:	Smoking cessation
Dosage Forms	:	Tablet, Chew gum, Patch

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT NICOTEX NICOTINE

Is NICOTEX NICOTINE suitable for under 18 years of age?

No. it is not recommended for children and adolescents below 18 years of age. Consult your doctor for advice.

What is the use of NICOTEX NICOTINE?

It is a trans-dermal/skin patch that helps you quit smoking using the principle of Nicotine Replacement Therapy (NRT). The patch when placed on your body gradually releases nicotine throughout the day.

Are there any specific conditions where I should be cautious before taking NICOTEX NICOTINE?

It should be used only when advised by the doctor. Patients with cardiac disorders, diabetes, gastrointestinal disease, and liver or kidney problems should be cautious before using this patch.

REFERENCES

1. KD Tripathi MD. Drugs acting on ANS. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page - 122.

2. Charles P O Brien. Drug Addiction. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 657.

3. Keliane Liberman, Peter Van Schuerbeek, Sarah Herremans, Marc Meysman, Johan De Mey and Nico Buls. The effect of nicotine patches on craving in the brain: A functional MRI study on heavy smokers, Sep 2018; [Accessed Oct 7, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181594/

4. Glaxo SmithKlin. Dec 5, 2011, [Revised Oct 10, 2018] [Accessed Oct 7, 2020] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=93b2d1b9-83c1-40b5-b6af-90c38c8d6cef

5. Novartis consumer Health Inc, 2014, U.S. Food & Drug Administration [Accessed Oct 7, 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020076orig1s036lbl.pdf

6. Clonmel Healthcare Ltd. [Revised Sep 2019] [Accessed Oct 7, 2020] https://www.hpra.ie/img/uploaded/swedocuments/a9c498ae-d679-4319-98b7-ced77aac1c4d.pdf

7. McNeil Products Ltd (UK), Electronic Medicines Compendium (EMC); [Revised Sep 2020] [Accessed Oct 7, 2020] https://www.medicines.org.uk/emc/files/pil.1323.pdf