INTRODUCTION

CANESTEN contains a medicine called clotrimazole which belongs to the group of medicines called azole antifungal agents. It is indicated for the management and prevention of fungal skin infections such as athlete’s foot, tinea cruris, ringworm, tinea versicolor, diaper rash and fungal sweat rash. It helps to soothe the irritated skin and protects your skin from chafing and rash. It is highly useful in areas wherever excess perspiration of exudates need absorption.

Clotrimazole acts by blocking the biosynthesis of fungal ergosterol which leads to the disruption of fungal cell membrane and inhibition of fungal growth. This medicine is for external use only. Your doctor will decide the duration of the therapy depending upon the type of the infection. Do not stop using this medicine abruptly without consulting your doctor as it may leads to recurrence of the infection.

Along with the management, try to keep the infected area clean by washing it daily. Try not to share your towels and bathmats with other people, as it could prevent the spread of infection. In case of having athlete’s foot, always try to keep your feet and toes dry. Always wash your socks and tights thoroughly in hot water. If possible, change your footwear daily. Although you may feel itching in the infected area, avoid scratching vigorously as it may damage your skin and cause the infection to spread further.

CANESTEN is generally safe and well tolerated. However, it may cause application site redness, swelling, itching and burning in some individuals. They are usually mild and temporary and vanishes with therapy. This medicine should be used with caution in pregnant or breastfeeding women and in children under 18 years of age. Consult your doctor before taking.

USES OF CANESTEN

• Manages fungal skin infections such as athlete’s foot, tinea cruris, ringworm, tinea versicolor and diaper rash

HOW CANESTEN WORKS

Clotrimazole exerts its antifungal activity by inhibiting the biosynthesis of ergosterol, an essential constituent of fungal cell membrane which helps to keep the fungal cell intact and directly promotes its growth. Inhibition of ergosterol biosynthesis damages the fungal cell integrity and leads to the inhibition of fungal growth.

DIRECTIONS FOR USE

Use this medicine as directed by your physician. It is for external use only. Wash the affected area thoroughly and pat it dry. Dab the required amount of powder on the affected areas. Do not cover the manageed areas. Your doctor will decide the duration of therapy for you depending upon the severity of your condition. Avoid contact of this medicine with your eyes. If contact happens, rinse it thoroughly with water. Continue to use this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF CANESTEN

HOW TO MANAGE SIDE EFFECTS

Application site reactions:

Avoid hot showers because hot water can irritate the skin. Do not use perfumed soaps or vaginal deodorants. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Wear cotton underwear and loose-fitting clothes and change your sanitary protection regularly. Regularly use moisturizers to soothe and hydrate the affected area. If the symptoms still persist, contact your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor about all the medicines you use, including non-prescription and prescription medicines, and herbal supplements.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Do not store above 25°C

FAQs ABOUT CANESTEN

Can CANESTEN be used in babies?

Yes. This medicine can be used in babies to manage diaper rash. However, consult your doctor before application.

Can CANESTEN be used to manage pimples?

No. This medicine is only used to manage fungal skin infections such as athlete’s foot, ringworm, fungal nappy rash, fungal sweat rash and thrush.

Can I stop using CANESTEN suddenly?

No. Do not stop using this medicine abruptly without consulting your doctor as it may leads to recurrence of the infection.

REFERENCES

1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 792.

2. John E. Bennett. Antifungal agents. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1587.

3. Gerald G. Briggs and Roger K. Freeman. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 895-897.

4. Rasthawathana Desomchoke, Sumanas Bunyaratavej, Charussri Leeyaphan, Nuntida Prasertworonun, Chuda Rujitharanawong, Lalita Matthapan, Penvadee Pattanaprichakul. Efficacy and Safety in 1% Clotrimazole Powder, Adjuvant Therapy in Patients with Superficial Fungal Cutaneous Infection in Intertriginous Areas. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. December 2016. [Accessed 20th January 2021] https://pubmed.ncbi.nlm.nih.gov/29953171/

5. P. Ongsri, Sumanas Bunyaratavej, Mahidol University, C. Leeyaphan, Penvadee Pattanaprichakul and Mahidol University. Efficacy of antifungal cream versus powder in the management of fungal foot skin infection and unpleasant foot odor at medical department of thai naval rating school. ResearchGate. March 2018. [Accessed 20th January 2021] https://www.researchgate.net/publication/328572585_Efficacy_of_antifungal_cream_versus_powder_in_the_management_of_fungal_foot_skin_infection_and_unpleasant_foot_odor_at_medical_department_of_thai_naval_rating_school

6. Palsons Derma Pvt Ltd. KANSEL Dusting powder. Palsonsderma.com. [Accessed 20th January 2021] https://www.palsonsderma.com/kansel-dusting-powder

7. Hetero healthcare limited. IMIDIL DUSTING POWDER. Heterohealthcare.com. Accessed 20th January 2021] https://www.heterohealthcare.com/imidil-dusting-powder